The complement system has evolved during the past 1.2 billion years, making it one of the oldest parts of the immune system. Since its discovery around 100 years ago, the system has been mainly...

Platelets contribute to the regulation of tissue neovascularization, although the specific factors underlying this function are unknown. Here, we identified the complement anaphylatoxin C5a-mediated...

On April 29th, the Immunology Day is celebrated around the world. The motto in 2021 is COVID-19. The German Society for Immunology has compiled a lot of interesting material regarding the immune...

Arthritis typically involves recurrence and progressive worsening at specific predilection sites, but the checkpoints between remission and persistence remain unknown. Here,we defined themolecular...

Food allergies are common, costly and potentially life-threatening disorders. They are driven by Th2, but inhibited by Th1 reactions. There is also evidence indicating that IL-2 agonist treatment...

Highlights • MHC associated susceptibility represent the most prevalent genetic risk factors for the development of autoimmune diseases. This study uncovered a novel link between the MHC haplotype...

Allergic asthma is a chronical pulmonary disease with high prevalence. It manifests as a maladaptive immune response to common airborne allergens and is characterized by airway hyperresponsiveness,...

German-American research team has demonstrated a novel role of the complement system in brain aging process As people get older, structures and functions in the brain change. An important age-related...

The COVID-19 pandemic keeps the world in suspense uniting clinicians and basic researchers in their efforts to better understand disease pathogenesis and develop effective clinical interventions. The...

The European Union will fund the doctorate programme CORVOS for the next 4 years with 4.1 million Euros for by the Horizon 2020 programme. CORVOS stands for COmplement Regulation and Variations in...