Welcome to the ISEF

The Institute for Systemic Inflammation Research (ISEF) was founded in 2008 as a research institute within the medical section of the University of Lübeck (UzL). The ISEF is dedicated to delineate the cellular and molecular mechanisms underlying dysregulated innate and adaptive immune responses in allergic, autoimmune and infectious diseases. For this purpose, we use in vitro and in vivo experimental disease models. Ultimately, we strive to translate such knowledge and advances into new diagnostic, preventive and therapeutic approaches.

Our vision –
for a better understanding of immunology


Björn Laffer, Malte Lenders, Elvira Ehlers-Jeske, Karin Heidenreich, Eva Brand, Jörg Köhl  PMID: 38304433 PMCID: PMC10830671 DOI: 10.3389/fimmu.2024.1307558 Abstract Defective a-galactosidase A...
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Gopalan Gnanaguru 1, Steven J Tabor 1, Gracia M Bonilla 2, Ruslan Sadreyev 2, 3, Kentaro Yuda 1, Jörg Köhl 4 5, Kip M Connor 1 Affiliations expand PMID: 36762625  PMCID: PMC10110418 (available on...
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