• ISEF Research institute within the medical section of the University of Lübeck (UzL)

Welcome to the ISEF

The Institute for Systemic Inflammation Research (ISEF) was founded in 2008 as a research institute within the medical section of the University of Lübeck (UzL). The ISEF is dedicated to delineate the cellular and molecular mechanisms underlying dysregulated innate and adaptive immune responses in allergic, autoimmune and infectious diseases. For this purpose, we use in vitro and in vivo experimental disease models. Ultimately, we strive to translate such knowledge and advances into new diagnostic, preventive and therapeutic approaches.

Our vision –
for a better understanding of immunology

News

Food allergies are common, costly and potentially life-threatening disorders. They are driven by Th2, but inhibited by Th1 reactions. There is also evidence indicating that IL-2 agonist treatment...
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Highlights • MHC associated susceptibility represent the most prevalent genetic risk factors for the development of autoimmune diseases. This study uncovered a novel link between the MHC haplotype...
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