Welcome to the ISEF

The Institute for Systemic Inflammation Research (ISEF) was founded in 2008 as a research institute within the medical section of the University of Lübeck (UzL). The ISEF is dedicated to delineate the cellular and molecular mechanisms underlying dysregulated innate and adaptive immune responses in allergic, autoimmune and infectious diseases. For this purpose, we use in vitro and in vivo experimental disease models. Ultimately, we strive to translate such knowledge and advances into new diagnostic, preventive and therapeutic approaches.

Our vision –
for a better understanding of immunology

News

The complement system has evolved during the past 1.2 billion years, making it one of the oldest parts of the immune system. Since its discovery around 100 years ago, the system has been mainly...
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Platelets contribute to the regulation of tissue neovascularization, although the specific factors underlying this function are unknown. Here, we identified the complement anaphylatoxin C5a-mediated...
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