The Köhl lab is interested in the biology of the complement system. A particular focus is on the multiple functions of the small cleavage fragments of C3 and C5, i.e. the anaphylatoxins (AT) C3a and...

My group is interested in settings in which complement, or more specifically the anaphylatoxin C5a and the corresponding receptors C5aR1 and C5aR2, are involved in regulating immune responses or...

Allergic asthma is one of the most prevalent diseases of the western world. It develops in genetically susceptible individuals as a chronic inflammatory disorder of the upper airways leading to...

The research group focuses on terminal differentiation of B lymphocytes into plasma cells and the role of these cells in inflammatory diseases. Through the secretion of antibodies, plasma cells...

Complement is undeniably quintessential for innate immunity by detecting and eliminating infectious microorganisms. We have highlighted an equally profound impact of complement on adaptive immunity...